Frequently asked questions
A resting phase after embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer is often recommended for patients undergoing medically assisted procreation. Previously, gynecologists of the CPMA had adopted this attitude and asked the patients to rest between 20 and 30 minutes after embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer.
The benefit of a resting phase after the transfer was however questioned by several studies (1,2,3,4). More specifically, two prospective studies, based on a large number of patients showed objectively that the chances of pregnancy were similar whether patients remained lying down or if they rose immediately after embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer (3,4). On the other hand, fear that the embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. could be expelled by rising proved unfounded, as the standing position did not induce displacement of the embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. inside the uterine cavity (5). In light of these studies, we decided not to recommend systematic rest after embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer.
(1) Sharif et al. (1998) Is bed rest following embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer necessary ? Fertil Steril 69: 478-481
(2) Amarin et al. (2004) Bed rest versus free mobilisation following embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer : a prospective randomised study. BJOG 111:1273-1276
(3) Bar-Hava et al. (2005) Immediate ambulation after embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer: a prospective study. Fertil Steril 83: 594-597
(4) Purcell et al. (2007) Bed rest after embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer: a randomized controlled trial. Fertil Steril 87: 1322-1326
(5) Wolcott and Stanger (1998) Ultrasound tracking of the movement of embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo.-associated air bubbles on standing after transfer. Human Reprod 13: 2107-2109
Freezing can, through the formation of ice crystals, induce damage in the structure of cryopreserved cells. Despite all the precautions taken, the damage is sometimes irreversible and results in lysis of the zygoteImpregnated oocyte, also called the "two pronuclei stage", about 20 hours after the spermatozoa has penetrated into the oocyte. The male and female pronuclei are visible in the oocyte, which has not yet divided to form what is then called an embryo. or a non-resumption of cleavage. These alterations may be related to the technique, but also to the potential of development of each zygoteImpregnated oocyte, also called the "two pronuclei stage", about 20 hours after the spermatozoa has penetrated into the oocyte. The male and female pronuclei are visible in the oocyte, which has not yet divided to form what is then called an embryo.. A statistical analysis of our data since 2001 indicates that 76.4% (5360/7018) zygotes survived freezing and accomplish their first cell cleavage. EmbryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer was achieved in 93.3% of the cryo cycles (2926/3136) and 10.5% of transferred embryos led to the formation of an EmbryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. sac (544/5181). These global results must be adjusted, as for fresh embryos, according to the woman's age.
According to the LPMAThe Swiss Law on Medically Assisted Procreation (2001)., the Swiss law on Medically Assisted Procreation, cryopreserved zygotes may be kept for a maximal duration of 5 years.
See the article 16 of the LMPA
Treatment costs vary considerably. Some are covered by the health insurances, others do not. Talk to your doctor. Regarding the IVF procedures, you can get a price list under Costs.
Some doctors perform the embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer under ultrasound guidance. Under these conditions a full bladder allows an easier localization of the uterusPear-shaped organ that contains and nourishes the fetus during pregnancy, which contracts in a powerful and rhythmic manner at birth to expel the fetus. and cervixLower part of the uterus, adjacent to and reaching into the vagina, which secretes an alkaline mucus to protect the sperm from acidic environment of the vagina.. If you get to the laboratory with an empty bladder, drinking one or two glasses of water will be sufficient.
The minimal duration is 14 days, which means until the first pregnancy test. It is important not to interrupt the treatment without medical advice, but the precise time of administration is not critical, as long as the prescribed dose is not modified.
Your physician will determine the appropriate manner to detect your ovulationThe release of the egg from the ovary. A mature follicle bursts, expelling the egg it contains into the fallopian tube. This usually occurs around the middle of the menstrual cycle. in your personal situation. If he proposes that you follow your cycle with OVU-LHLuteinizing hormone. Hormone secreted by the pituitary gland, triggering on the one hand the expulsion of the ovum by the mature follicle and stimulating on the other hand the production of progesterone by the corpus luteum. tests, the medical assistants can give you the explanations. You can also find practical advice on this website under Tests OVU-LH.
Several international studies have shown that ICSIFrom English "Intra-Cytoplasmic Sperm Injection." Assisted fertilization by microscope, where a single sperm is injected directly into the oocyte. ICSI is indicated in cases of male fertility problems, so if there are only very few normal sperm in the sperm or the fertilization capacity of sperm is extremely small. does not present more risks than IVF. It should be noted however that the method is still new. The first ICSIFrom English "Intra-Cytoplasmic Sperm Injection." Assisted fertilization by microscope, where a single sperm is injected directly into the oocyte. ICSI is indicated in cases of male fertility problems, so if there are only very few normal sperm in the sperm or the fertilization capacity of sperm is extremely small. baby was born in the early 1990s. As ICSIFrom English "Intra-Cytoplasmic Sperm Injection." Assisted fertilization by microscope, where a single sperm is injected directly into the oocyte. ICSI is indicated in cases of male fertility problems, so if there are only very few normal sperm in the sperm or the fertilization capacity of sperm is extremely small. is often performed for reasons pertaining to the man, it is possible that a boy will inherit his father's genes that control the production of spermEjaculated spermatozoa and secretions during the male orgasm.. If the defect observed in the father has a genetic origin, it is almost certain that the child will inherit the defect if it is located on the Y chromosome.
The choice of IVF or ICSIFrom English "Intra-Cytoplasmic Sperm Injection." Assisted fertilization by microscope, where a single sperm is injected directly into the oocyte. ICSI is indicated in cases of male fertility problems, so if there are only very few normal sperm in the sperm or the fertilization capacity of sperm is extremely small. is discussed with you by the doctor in charge of your treatment. This choice is quite rarely made at the time of inseminationProcess to facilitate the meeting of spermatozoon and egg. Using a catheter, semen prepared for this purpose is brought directly into the uterus..
Generally, IVF is carried out when all spermEjaculated spermatozoa and secretions during the male orgasm. tests are good or when the spouse has initiated a spontaneous pregnancy.
ICSIFrom English "Intra-Cytoplasmic Sperm Injection." Assisted fertilization by microscope, where a single sperm is injected directly into the oocyte. ICSI is indicated in cases of male fertility problems, so if there are only very few normal sperm in the sperm or the fertilization capacity of sperm is extremely small. will be offered in circumstances where, according to our current experience, a failure of fertilizationFusion of an egg and a spermatozoon, fertilization occurs naturally in the fallopian tubes. can be anticipated (reduced spermEjaculated spermatozoa and secretions during the male orgasm. quality, repeated inseminationProcess to facilitate the meeting of spermatozoon and egg. Using a catheter, semen prepared for this purpose is brought directly into the uterus. failures or long-standing idiopathic infertilityThis term is used when the cause of infertility of a couple remains unknown even after thorough medical examination.)
The optimal duration of sexual abstinence is less than 5 days and ejaculation should not occur within 24 hours before an inseminationProcess to facilitate the meeting of spermatozoon and egg. Using a catheter, semen prepared for this purpose is brought directly into the uterus. or an egg retrieval. Outside these limits, there is no contraindication to sexual activity during an ART treatment. If you have questions, please speak with your doctor.
The laboratory is accredited according to ISO / IEC 17025, which requires the use of strict procedures. For example, it is forbidden to place on the same desk gametesMale and female reproductive cells *: spermatozoa and eggs. from two couples. Of course, all tubes or culture dishes are provided with labels bearing the names of both spouses, this from the time of harvest until inseminationProcess to facilitate the meeting of spermatozoon and egg. Using a catheter, semen prepared for this purpose is brought directly into the uterus. or transfer. Through this rigorous protocol, the confusion of gametesMale and female reproductive cells *: spermatozoa and eggs. are reduced to maximum. The laboratory team is at your disposal to answer your questions, if any.
Many pregnancies were obtained from cryopreserved zygotes. There is no decrease in the chances of pregnancy during the 5 years of cryopreservationProcess for the preservation of eggs and sperm by freezing. Thanks to the cryopreservation of zygotes the risk of multi-fetal pregnancy after IVF and ICSI can be reduced and the patient doest not need to repeat the hormonal stimulation and the collection of oocytes. allowed by the LPMAThe Swiss Law on Medically Assisted Procreation (2001)..
The answer is clearly "no." As a teenager, the number of oocytes is about 400,000 and a woman ovulates about 450 times throughout her life. The number of oocytes spontaneously disappearing is the leading cause of ovarian activity loss.
During each menstrual cycle, several follicles are ready to begin maturation in each ovary. These"selected" follicles are the only ones sensitive to the drugs used to stimulate their growth. For example, in a natural cycle, several follicles are selected, but only one matures, while the others enter atresia and are eliminated. In a stimulated cycle, all selected follicles are sensitive to the administered hormonesSubstances secreted by the endocrine glands. Hormones act as chemical messengers for regulating metabolic processes throughout the body. and have a chance to mature.
CPMA, Rue de la Vigie 5, 1003 Lausanne, tél: 021 321 15 80