Frequently asked questions

Are there any discussion groups for patients?

Yes, the CPMA organises Discussion groups for people confronted with fertility problems:

Rencontres à thème (sorry, in French only)

Groupes de rencontre pour personnes confrontés au don de sperme ou d'ovocyte (sorry, in French only)

How long should I rest after an embryo transfer?

A resting phase after embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer is often recommended for patients undergoing medically assisted procreation. Previously, gynecologists of the CPMA had adopted this attitude and asked the patients to rest between 20 and 30 minutes after embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer. 

The benefit of a resting phase after the transfer was however questioned by several studies (1,2,3,4). More specifically, two prospective studies, based on a large number of patients showed objectively that the chances of pregnancy were similar whether patients remained lying down or if they rose immediately after embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer (3,4). On the other hand, fear that the embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. could be expelled by rising proved unfounded, as the standing position did not induce displacement of the embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. inside the uterine cavity (5). In light of these studies, we decided not to recommend systematic rest after embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer.

(1) Sharif et al. (1998) Is bed rest following embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer necessary ? Fertil Steril 69: 478-481

(2) Amarin et al. (2004) Bed rest versus free mobilisation following embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer : a prospective randomised study. BJOG 111:1273-1276

(3) Bar-Hava et al. (2005) Immediate ambulation after embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer: a prospective study. Fertil Steril 83: 594-597

(4) Purcell et al. (2007) Bed rest after embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo. transfer: a randomized controlled trial. Fertil Steril 87: 1322-1326

(5) Wolcott and Stanger (1998) Ultrasound tracking of the movement of embryoTerm designating the early stages of development from conception to the eighth week of pregnancy. From the first cell division on, the two-cell stage, one uses the term embryo.-associated air bubbles on standing after transfer. Human Reprod 13: 2107-2109

How long must Utrogestan treatment be continued after embryo transfer?

The minimal duration is 14 days, which means until the first pregnancy test. It is important not to interrupt the treatment without medical advice, but the precise time of administration is not critical, as long as the prescribed dose is not modified. 

How to use OVU-LH tests for detecting ovulation?
What are the risks of ICSI?

Several international studies have shown that ICSIFrom English "Intra-Cytoplasmic Sperm Injection." Assisted fertilization by microscope, where a single sperm is injected directly into the oocyte. ICSI is indicated in cases of male fertility problems, so if there are only very few normal sperm in the sperm or the fertilization capacity of sperm is extremely small. does not present more risks than   IVFIVF or In Vitro Fertilization: Fertilization outside of the body, for which one induces with gonadotrophins the development of several ovarian follicles. The oocytes (eggs) arrive at maturity and are taken from the ovary by surgical puncture and mixed 4-6 hours later with the sperm of the partner (or ICSI is performed to introduce one spermatozoa in each oocyte). To allow cell division, the fertilized eggs are kept from 2 to 6 days in a protected environment (incubator). The embryos are then transferred into the uterus of the patient for implantation.. It should be noted however that the method is still new. The first    ICSIFrom English "Intra-Cytoplasmic Sperm Injection." Assisted fertilization by microscope, where a single sperm is injected directly into the oocyte. ICSI is indicated in cases of male fertility problems, so if there are only very few normal sperm in the sperm or the fertilization capacity of sperm is extremely small.   baby was born in the early 1990s. As ICSIFrom English "Intra-Cytoplasmic Sperm Injection." Assisted fertilization by microscope, where a single sperm is injected directly into the oocyte. ICSI is indicated in cases of male fertility problems, so if there are only very few normal sperm in the sperm or the fertilization capacity of sperm is extremely small. is often performed for reasons pertaining to the man, it is possible that a boy will inherit his father's genes that control the production of spermEjaculated spermatozoa and secretions during the male orgasm.. If the defect observed in the father has a genetic origin, it is almost certain that the child will inherit the defect if it is located on the Y chromosome.

 

When does one use IVF or ICSI?

The choice of IVFIVF or In Vitro Fertilization: Fertilization outside of the body, for which one induces with gonadotrophins the development of several ovarian follicles. The oocytes (eggs) arrive at maturity and are taken from the ovary by surgical puncture and mixed 4-6 hours later with the sperm of the partner (or ICSI is performed to introduce one spermatozoa in each oocyte). To allow cell division, the fertilized eggs are kept from 2 to 6 days in a protected environment (incubator). The embryos are then transferred into the uterus of the patient for implantation. or ICSIFrom English "Intra-Cytoplasmic Sperm Injection." Assisted fertilization by microscope, where a single sperm is injected directly into the oocyte. ICSI is indicated in cases of male fertility problems, so if there are only very few normal sperm in the sperm or the fertilization capacity of sperm is extremely small. is discussed with you by the doctor in charge of your treatment. This choice is quite rarely made at the time of inseminationProcess to facilitate the meeting of spermatozoon and oocyte (egg). Using a catheter, semen prepared for this purpose is brought directly into the uterus..
Generally, IVFIVF or In Vitro Fertilization: Fertilization outside of the body, for which one induces with gonadotrophins the development of several ovarian follicles. The oocytes (eggs) arrive at maturity and are taken from the ovary by surgical puncture and mixed 4-6 hours later with the sperm of the partner (or ICSI is performed to introduce one spermatozoa in each oocyte). To allow cell division, the fertilized eggs are kept from 2 to 6 days in a protected environment (incubator). The embryos are then transferred into the uterus of the patient for implantation. is carried out when all spermEjaculated spermatozoa and secretions during the male orgasm. tests are good or when the spouse has initiated a spontaneous pregnancy.
ICSIFrom English "Intra-Cytoplasmic Sperm Injection." Assisted fertilization by microscope, where a single sperm is injected directly into the oocyte. ICSI is indicated in cases of male fertility problems, so if there are only very few normal sperm in the sperm or the fertilization capacity of sperm is extremely small. will be offered in circumstances where, according to our current experience, a failure of fertilizationFusion of an egg and a spermatozoon, fertilization occurs naturally in the fallopian tubes. can be anticipated (reduced spermEjaculated spermatozoa and secretions during the male orgasm. quality, repeated inseminationProcess to facilitate the meeting of spermatozoon and oocyte (egg). Using a catheter, semen prepared for this purpose is brought directly into the uterus. failures or long-standing idiopathic infertilityThis term is used when the cause of infertility of a couple remains unknown even after thorough medical examination.)

What is the ideal abstinence length before an ART treatment?

The optimal duration of sexual abstinence is less than 5 days and ejaculation should not occur within 24 hours before an inseminationProcess to facilitate the meeting of spermatozoon and oocyte (egg). Using a catheter, semen prepared for this purpose is brought directly into the uterus. or an egg retrieval. Outside these limits, there is no contraindication to sexual activity during an ART treatment. If you have questions, please speak with your doctor.

Is there a risk of confusing the identification of gametes?

The laboratory is accredited according to ISO / IEC 15189, which requires the use of strict procedures. For example, it is forbidden to place gametesMale and female reproductive cells *: spermatozoa and eggs. from two couples on the same table. Of course, all tubes or culture dishes are provided with labels bearing the names of both partners, from the time of spermEjaculated spermatozoa and secretions during the male orgasm. procurement and oocyteA female reproductive cell. At birth, the ovaries contain 1 to 2 million oocytes. At puberty, there are no more than 400'000 to 500'000 left. Only 400 to 500 will reach maturity and ovulation at a rate of  one per month until menopause. All the others will finally degenerate at various stages of development. pick-up until the transfer in utero. Through this rigorous protocol, the possible confusion of gamete identification is reduced to a minimum. The laboratory team is at your disposal to answer any questions.

What is the cryopreservation duration of zygotes and embryos?

According to the LPMAThe Swiss Law on Medically Assisted Procreation (2001)., the Swiss law on Medically Assisted Procreation, frozen zygotes and embryos may be cryopreserved for a duration of 5 years, which can be prolonged for another 5 years on the couple's request.

Do frozen zygotes loose their development aptitude with time?
Do stimulations induce early menopause?

The answer is clearly "no." As a teenager, the number of oocytes is about 400,000 and a woman ovulates about 450 times throughout her life. The number of oocytes spontaneously disappearing is the leading cause of ovarian activity loss.

During each menstrual cycle, several follicles are ready to begin maturation in each ovary. These"selected" follicles are the only ones sensitive to the drugs used to stimulate their growth. For example, in a natural cycle, several follicles are selected, but only one matures, while the others enter atresia and are eliminated. In a stimulated cycle, all selected follicles are sensitive to the administered hormonesSubstances secreted by the endocrine glands. Hormones act as chemical messengers for regulating metabolic processes throughout the body. and have a chance to mature.

CPMA, Rue de la Vigie 5, 1003 Lausanne, tél: 021 321 15 80